Positions:Postdoctoral researcher

Department: Plant Cell Biotechnology, CPSBB

His early work focused on the biosynthesis of high-valuable secondary metabolites using plant in vitro systems as a production platform. Dr. Marchev has developed extensive expertise in plant biotechnology. The main area of Dr. Marchev’s research comprises the application of plant biotechnology tools and bioprocess engineering technologies in modulation of secondary metabolism in plant cells and tissue cultures at laboratory scale, as well as, metabolite profiling by NMR spectroscopy. Dr. Marchev is also interested in studying the antineoplastic potential of plant extracts and pure molecules in cancer cell lines.

 SELECTED PUBLICATIONS:

Marchev A., Yordanova Z., Georgiev M. (2020) Green cell factories for advanced production of plant secondary metabolites. Submitted in Critical Reviews in Biotechnology.

Amirova K., Dimitrova P., Marchev A., Aneva Y., Georgiev M. (2019) Clinopodium vulgare L. (wild basil) extract and its active constituents modulate cyclooxygenase-2 expression in neutrophils. Food and Chemical Toxicology, 124:1-9. https:// doi: 10.1016/j.fct.2018.11.054.

Marchev A., Dimitrova P., Burns A., Kostov R., Dinkova-Kostova A., Georgiev M. (2017) Oxidative stress and chronic inflammation in osteoarthritis: can NRF2 counteract these partners in crime? Annals of the New York Academy of Sciences, 1401(1):114-135. https:// doi: 10.1111/nyas.13407.

PlantaSYST has received funding from the European Union’s Horizon 2020 research and innovation programme (SGA-CSA No 664621 and No 739582 under FPA No. 664620)


Calls: H2020-WIDESPREAD-2014-2015, Topic: WIDESPREAD-1-2014: Teaming, and H2020-WIDESPREAD-2016-2017, Topic: H2020-WIDESPREAD-01-2016-2017: TeamingPhase2